I certainly don't have a problem with this (as if Mongoose needed my permission) but I do wonder if the OTU can survive the upgrade. It's so obviously a middle sixties (late 50s?) SF background that ... well I don't know if you can incorporate nanotechnology, massive electronics changes into the game. 3D printers, for instance, would seem to be a major change. Why do you need trade in such a universe? Sell the programs yes, but once you can make your own... why import? And 3D printers can make themselves so production will increase. Of course the printers do require raw materials (or raw materials that have been processed) and wet nanotechnolgy also requires processed raw materials so there might well be a market for that but I would think in the mega or giga tonnage.
That's my experience also. When running an OTU game I find I have to constantly tell players, "well, according to the setting, you can't do that". And that's not good. Modern players have different expectations out of a sci fi setting than the OTU supplies.
It's no the basic precepts, which is neo-feudal politics, 1 week jump, and no FTL comms. They're easy to spell out. It's all the other stuff that came out of expressions of the rules, like house sized computers and 'no nanotech'. Since there is a very vocal minority of old timers that cannot abide changes from the CT era setting, it becomes difficult modernise or reform the Original Traveller Setting.
Personally, I think Mongoose should go ahead and update the OTU for modern expectations from its core market. It's already doing that somewhat in subtle ways by introducing new gear and functionality in the main books (magrails notwithstanding ), and given that (hopefully) a lot of new OTU material will come out of the Foreven license, it seems the Classic setting is getting the 'freeing up' it deserves.