It would seem that conventional (non speed of light energy) direct fire weapons would be pretty useless at typical orbit speeds (interplanetary space either for that matter) unless you matched course and speed of your target and got up really close. I suppose that is a possibility for security vehicles and the like but its not likely your target is going to just sit there and let you. Unless they were disabled or out of fuel of something it would be a really rare occurrence.
The problem with conventional weapons is countering the inherent velocities of the targets. They can either be completely useless of extremely devastating.
The closing velocities of ships, especially in space, can be extremely high, giving kinetic energy weapons a high potential. The game, as you mentioned is getting them to connect, and that is easier said that done. Also, particularly pertaining to 2300 and Stutterwarp, in deep space, SW ships don't really "have" momentum. They're there or they're not. In a normal Newtonian system like regular Traveller, it's a different story.
As a rule, GDW has dodged this problem, they simply don't address it, especially at space levels.
Given this, I suppose only energy weapons would be mounted on any space vehicle unless they had an atmospheric role as well.
In 2300, Spaceships aren't really an intermodal as ships in normal Traveller. Getting out of the gravity well is still a major problem for 2300. And the SW ships tend to orbit high out of the atmosphere where normal planes are efficient, fast, and powerful. The ships one the ground don't work in orbit, and vice a versa. In normal Traveller, streamlined ships can interface and work just fine in a terrestrial setting as well as in orbit, so adding conventional weapons to a "close support" ship (a small ship, a ships boat, something like that) can make a lot of sense. But not so much in 2300.
Would it also be safe to assume that given the really limited and predictable maneuvering of spacecraft, any computer assisted weaponry is going to achieve and automatic hit? If given a few seconds to locate an target, develop a fire solution, align your weapon and fire... seems it would have to it. Not much of an element of chance, or skill for that matter (above being able to operate the equipment)
Light speed weapons truly trivialize what before is a rather complicated ballistics problem. So now it's a detection and tracking problem -- ensuring that the bright blot on the sensor is in fact the target you want to hit, and tracking the weapon to that coordinate.
The Moon, for example, is a bit over a light second away. So, anything in orbit between the Earth and the Moon can be hit in less than a second once the weapon is fired. Add to that the fact that ships are "big" and it makes the problem that much easier. Compounded with a ship locked in to its current course without the ability inject significant delta V, then the math becomes pretty simple.
So the only real hope is to cloud the sensors perhaps through EW to convince it to hit something else. Then you hope they don't have more than one weapon.
Why, it's the drunk piano player. You're so drunk, you can't hit nothin'. In fact, you're probably seeing double.
I have two guns, one for each of ya.