I think that if someone was going to build a spherical ship, with a nod to living in it for a long while (read a week), then having some kind of long, slow spiral ramp might be more useful to connect the decks than a tube shaft. I couldn't see it in a 100-200 dton ship, but perhaps something larger.
Why a spiral ramp? A long continuous tunnel allows for more exercise and more "natural" living space, not to mention that the rooms could be oriented a little differently.