I do like the idea of ships having a constant acceleration/deceleration of at least 1-G for 100 or so hours... Is this possible with handwavely-efficient plasma rockets? (i.e. the same level of handwave as my fusion torches' efficiency)?
You're wanting a delta-V of 100*3600*9.8 or so... so ∆v=3528000
Given the rocket equation ∆v=Ve * Ln(Mf/Md)
M (full or dry) mass
and 95% mass is fuel, 100/5=20/1
Ln(20)=2.995732273553991
3,528,000 = Ve * 2.995732273553991
Divide both sides by 2.995732273553991
3,528,000/2.995732273553991 = Ve
Ve ≅ 1,177,675.3...
Or an Isp of around 120,170.9
Note that current plasma thrusters run ISP of around 3000 (N-Star) to 5000 (Vasimir VX-200 running Argon).
So, for a more reasonable ship - say ony 40% fuel...
3,528,000 = Ve * Ln(10/6)
3,528,000 = Ve * 0.5108256237659907
3,528,000/0.5108256237659907 = Ve
Ve ≅ 6,906,466.4
Isp ≅ 704,741.5
That's some insane Isp. Ve in the 2.3 PSL range. You'd be causing a glow if your exhaust brushed atmosphere....
Personally speaking... It doesn't matter whether you power the magic thruster with Fusion or Fission - the problem is accelerating the exhaust. You're using a major particle accelerator for a drive at that ISP, and the power needs pretty much mean needing practical fusion.
The fusion rocket is estimated to have an ISP in the 130,000 range...
... which puts the Isp at 95% fuel in the fusion rocket range.