If the world is outside its star's 100D limit there is no most efficient path to the world. It is anywhere on the imaginary globe that is the planet's 100D limit.
If you take in to account all of the nuances of Jump: vector preservation, the 10% jump window, differential velocities between source and target worlds (including both orbital velocities and system velocities), potential jump masking and shadowing (if you honor that concept), then, yea, there actually are more efficient paths between systems that will potentially net a few hours of savings in travel. You can't control jump, but you can control the rest of it.
Since the bulk of traffic from most systems is limited to a few nearby systems, like the weather, "everyone" will know what those exit vectors are, it's "free" to use them, and saves them a few hours in space, why would they not choose them? If there's 3 common destinations, there may be up to 3 vectors of exodus. Similarly, since they are well known, free to use, they'd certainly be popular -- perhaps to the point that local traffic control strongly suggests to ships that they use those vectors, and thus the local Space Patrol can more efficiently patrol traffic mishaps and shenanigans.
Even for worlds deep within the 100D shadow of the local primary, there's always a "fastest" way out of the hole. If nothing else, it's radially away from the primary. And that's the way most traffic will choose. They aren't REQUIRED to choose those vectors, but they're just the best ones on any particular day, so don't be surprised to see a stream of ships heading that way.
Similarly, incoming vessels will be targeting arrival points that give them the best chance of arriving quickly. So, each day you'll see a cluster of ships flashing in to the systems, all in the same general areas. With the jump window, this area is spread out a bit more than the exodus, but the majority of traffic will cluster in these entry zones, that should be readily patrolled.
While you are certainly capable of choosing to arrive on the wrong side of the primary on any given day, few would consciously choose to do that. It's just a waste of time.