Life support: Travelling to and returning from Mars is more an engineering challenge not impossible, perhaps doable. Without gravity tech, landing ON Mars is a one way-trip until infrastructure is built to support return. Life support is the big hassle. Travel time is on the order of months, perhaps merely weeks. But we dont have cryofreezing, so you have to be awake. To breathe, eat and poop. We don't have terribly efficient recycling, so we have to bring more supplies.Except for Mars itself, I'd like to keep it real, in other words realistic technologies we could have in the 21st century, not Space 1999. Artificial gravity is for those shows that wanted to save money in not presenting zero-g but we have an unlimited special effects budget in our imagination. So if Mars had a breathable atmosphere, and Elon Musk were still around, what would we be doing right now? What would be the realistic thing?
We COULD launch unmanned depots, pre-positioned along the route, but that requires more infrastructure and coordination at first, back on Earth. Which may not be sustained after the Earth nukes itself.